Top 10 Companies in San Francisco (Ranked by Revenue and Market Value)

AllBlogThings Editors Published On:

TL;DR takeaways:

  • Uber and Salesforce remain the two revenue behemoths in San Francisco.
  • Block, DoorDash, and Airbnb are the next tier by revenue, with DoorDash's valuation reflecting a market eager for margin improvement and geographic expansion.
  • Watch Coinbase, Reddit, and DoorDash for the largest valuation moves: they are where narrative, regulation, and growth expectations collide.

Top 10 Companies in San Francisco (Ranked by Revenue and Market Value)

San Francisco is no longer just a scene for startups in Silicon Valley. It is home to a mix of enterprise software giants, platform plays, fintech incumbents, and fast-scaling marketplaces that together define the city's economic footprint.

This ranking of the "Top 10 Companies in San Francisco" pairs two lenses, one with trailing revenue and market value, so you can see which companies are actually selling services today and which ones the market is pricing for the future, and the other with their actual market value.

Below you will find:

  1. Two clear rank tables: one ordered by latest annual or trailing revenue, the other by market capitalization or latest valuation.
  2. A focused profile for each company with CEO, HQ confirmation, the revenue number used, and the market cap or valuation cited.
  3. An analytical section that explains the disconnects between revenue and valuation and what to watch for in 2026.

All figures are cited to primary filings, company releases, or market data published in 2025.

Where a company is private or reports nonstandard metrics, we note that and cite the estimate.

A quick summary table

The first fresh look at the companies topping today's list:

Top 10 in San Francisco by Revenue (trailing 12 months / latest published)

Rank Company HQ Revenue (latest annual or TTM)
1 Uber Technologies San Francisco $43.9 billion (2024)
2 Salesforce San Francisco $37.9 billion (Fiscal 2025)
3 Block Inc (formerly Square) San Francisco $24.12 billion (2024)
4 DoorDash San Francisco $11.9 billion (TTM to Jun 30, 2025)
5 Airbnb San Francisco $11.1 billion (2024)
6 Coinbase San Francisco (remote-first, major SF presence) $6.56 billion (2024)
7 Lyft San Francisco $5.8 billion (2024)
$6.11B TTM (mid-2025)
8 Twilio San Francisco $4.46 billion (FY 2024)
$4.73B TTM (mid-2025)
9 Instacart San Francisco $3.3 billion (2024)
$3.55B TTM (mid-2025)
10               Reddit San Francisco $1.3 billion (2024)
$1.66B TTM (mid-2025)

Revenue numbers use the latest company investor relations releases or the most recent full-year / trailing 12 months reported figures. Where companies report on a different fiscal calendar, we used the latest full-year or TTM numbers disclosed in investor materials, reliable market trackers, or the company's own reported FY or TTM metric. (Examples include Salesforce FY25 and Uber 2024 / Q2 2025 results).

For Coinbase, we include the contextual note that it has re-established a major SF office while operating a remote-first model; see the reports from CoStar and investor filings.

Top 10 Companies in San Francisco by Market Value / Valuation

This table we created with the snapshot, Sept 2025 market data, or the latest private valuation, so you can have another insightful look:

Rank Company Market cap / Valuation (approx)
1 Uber Technologies $197-206 billion (Sept 2025)
2 Salesforce $231 billion (Sept 2025)
3 Coinbase $83-84 billion (Sept 2025)
4 DoorDash $110 billion (Sept 2025)
5 Block Inc $45-48 billion (Sept 2025)
6 Airbnb $73-76 billion (Sept 2025)
7 Twilio $16 billion (Sept 2025)
8 Lyft $7-8 billion (Sept 2025)
9 Instacart private; ~mid-teens billions (secondary market estimates) - variable
10            Reddit public market cap ~ $49 billion (Sept 2025)
Earlier private valuations were much lower

Top 10 Companies in San Francisco Chart
Credits: AllBlogThings.com

Market capitalization is fluid, and the snapshot above uses market data providers and company investor releases in September 2025. Private valuations (Instacart, earlier private Reddit rounds) are estimates, and we mark them as such.

Profiles and what the numbers mean for each company

Below, we run through each company on the list, with the CEO, location of their headquarters, why the company ranks where it does, and the key revenue / market-value signals investors and operators should watch. So, hold tight and read more about these top SF companies in 2025:

1. Uber Technologies

  • CEO: Dara Khosrowshahi.
  • HQ: San Francisco.

Revenue: $43.9 billion (2024). "Revenue grew 18% YoY to $12.7 billion" in Q2 2025, per the company's shareholder release.

Market cap: roughly $197-206 billion in Sept 2025.

Why it's here as the #1 company in San Francisco: scale across mobility, delivery, and freight keeps gross bookings and revenue high. The business pairs thin margins per trip with massive transaction volume; revenue leadership reflects platform breadth more than unit profitability. Watch the rides vs delivery mix as a profit lever.

2. Salesforce

  • CEO: Marc Benioff (executive chair/CEO role ongoing; executive leadership in 2025 includes CFO changes).
  • HQ: San Francisco.

Revenue: $37.9 billion (Fiscal 2025). Salesforce guided FY26 revenue toward $40.5-40.9 billion.

Market cap: about $231 billion (Sept 2025).

Why it's here on the 2nd spot: recurring subscription revenue, large deal RPO, and heavy enterprise adoption of AI features (Agentforce, Data Cloud) sustained scale. The company is shifting to tighter AI integration as a growth catalyst while maintaining high margins on subscription revenue.

Quote from Salesforce materials: "Initiates revenue guidance of $40.5 billion to $40.9 billion."

3. Block Inc (Square)

  • CEO: Jack Dorsey (Chair and head; operational leadership includes Amrita Ahuja as CFO).
  • HQ: San Francisco.

Revenue: $24.12 billion (2024). TTM mid-2025 ~ $23.8B.

Market cap: ~$45-48 billion (Sept 2025).

Why it's here on the 3rd spot: Block's payments, Cash App, and BNPL (Afterpay) exposure give it high transactional revenue. For 2025 the business is stabilizing growth dynamics as Cash App and the seller ecosystem monetize more efficiently.

4. DoorDash

  • CEO: Tony Xu.
  • HQ: San Francisco.

Revenue: ~$11.9 billion TTM (to June 30, 2025). Q2 2025 revenue was $3.3 billion.

Market cap: ~$110 billion (Sept 2025).

Why it's here: delivery marketplace scaling and rising advertising revenue pushed margins up in 2025. The company is expanding via acquisitions and European rollouts; the EU approval of the Deliveroo takeover is a notable vote of confidence for cross-border expansion.

5. Airbnb

  • CEO: Brian Chesky.
  • HQ: San Francisco.

Revenue: $11.1 billion (2024). Q2 2025 revenue expanded to $3.1 billion.

Market cap: ~$73-76 billion (Sept 2025).

Why it's here: durable marketplace economics, high margins on service fees, and recurring host supply make Airbnb a resilient platform. Its revenue mix benefits from travel rebounds and higher ADR.

Here's what Airbnb says about the revenue:

"Revenue increased to $3.1 billion in Q2 2025 from $2.7 billion in Q2 2024."

6. Coinbase

  • CEO: Brian Armstrong. Headquarters and major operations anchored in San Francisco as it re-establishes large SF leases in 2025.

Revenue: $6.56 billion (2024) per company filings; TTM mid-2025 ~ $7.0B.

Market cap: ~$83-84 billion (Sept 2025).

Why it's here: crypto volatility drives lumpy revenue, but 2024 showed a major rebound in transaction volumes and revenue. The firm's valuation reflects renewed investor appetite for regulated infrastructure plays in crypto.

7. Lyft

  • CEO: David Risher (CEO since 2023).
  • HQ: San Francisco.

Revenue: ~ $5.8 billion (2024) / $6.11B TTM mid-2025.

Market cap: ~$7-8 billion (Sept 2025).

Why it's here: Lyft is smaller than Uber but has approached profitability and sustained revenue growth. Its moves into autonomous pilots and marketplace efficiencies are central to the story.

8. Twilio

  • CEO: [company leadership in 2025; CEO transitions have been public.
  • Twilio is headquartered in San Francisco.

Revenue: ~$4.46 billion (FY 2024) and ~ $4.73B TTM mid-2025.

Market cap: ~$16 billion (Sept 2025).

Why it's here: Twilio's developer APIs and communications layers are sticky B2B software revenue; growth is steady and margins are scaling with enterprise adoption.

9. Instacart (Maplebear / CART)

  • CEO: Fidji Simo (CEO since 2021).
  • HQ: San Francisco.

Revenue: $3.3 billion (2024) / TTM ~ $3.55B mid-2025.

Valuation/market cap: private/public market proxies have put Instacart in the mid-teens billions (varies by quarter).

Why it's here at the 9th spot: grocery is a lower margin than restaurants, but it is sticky. Instacart's revenue is from both delivery fees and merchant services; growth is stable.

10. Reddit

  • CEO: Steve Huffman.
  • HQ: San Francisco.

Revenue: $1.3 billion (2024); TTM mid-2025 ~ $1.66B.

Market cap: publicly traded Reddit was trading with a market cap near $49B in Sept 2025 (volatile since IPO).

Why it's here at the last spot: ad revenue growth in 2024-2025 accelerated sharply from a small base; Reddit's community data and unique conversational inventory make its ad growth an investor story. Overall, the company is too small to rank better.

Side-by-side: where revenue and valuation diverge

Two forces explain the difference between the revenue ranking and the valuation ranking that we used to rank these companies, and here we have an explanation for you:

  1. Public market narrative and multiple expansion. DoorDash, Coinbase, and Airbnb have strong market caps relative to revenue because investors are willing to pay for growth and margin expansion prospects. For example, DoorDash's valuation reflects both expanding ad revenue and international rollouts.
  2. Transactional vs. subscription businesses. Block and Uber are transaction-heavy; high revenue needs more infrastructure and sometimes yields lower multiples. Meanwhile, a smaller-revenue software business that is subscription-based can trade at higher multiples if margins are high and growth looks durable.
  3. Private company valuation opacity. Instacart and private secondary markets for firms like Stripe (not on the list) make valuation-based ranking noisy. We use publicly available secondary market estimates and company disclosures, marked clearly as estimates.

It should clear the doubts you may have.

What matters for 2026?

Well, we have three pragmatic signals:

  1. Profitability per transaction. The delivery and mobility companies' next inflection will be a higher net revenue margin driven by advertising, logistics automation, and reduced incentives. DoorDash's improving net revenue margin in Q2 2025 is a good example.
  2. Enterprise AI monetization. Salesforce and Block are embedding AI to grow Average Revenue Per User across enterprise customers. Salesforce's FY26 guidance and investments in Agentforce signal that executives expect AI to make enterprise suites stickier.
  3. Regulatory exposure and macro cycles. Coinbase's trajectory depends on crypto pricing and regulatory clarity; macro slowdowns reduce gross transaction volumes for payments/marketplaces. Keep revenue seasonality and regulation risk top of mind.

The companies are already heading to success for 2026 and are largely adapting Artificial Intelligence to boost revenue and cut costs.

Here's a list of our data sources for this list:

Uber

Salesforce

Airbnb

DoorDash

Instacart (Maplebear Inc.)

SoFi Technologies

Twilio

Lyft

Reddit

Block, Inc. (formerly Square)

That's all.

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AllBlogThings Editors

A dedicated team of news reporters, content editors, and trends explorers. Each an expert in our own respective categories. Our job is to make sure every article you read is worth your time. Publishing helpful and high quality content is our top priority.

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